Alex K Chen Posted June 3, 2020 Report Share Edit Posted June 3, 2020 Does anyone try it? See https://www.nature.com/articles/s41598-017-02419-3 for instance. I also know two very educated people in their 60s who have started taking it. Quote Link to comment Share on other sites More sharing options...
Alex K Chen Posted March 17, 2023 Author Report Share Edit Posted March 17, 2023 Quote Methods The redox agent methylene blue and the cell-permeable succinate prodrug NV118 were evaluated by measuring mitochondrial respiration and lactate production of human platelets exposed to metformin and co-treated with either of the two pharmacological bypass agents. Results The cell-permeable succinate prodrug NV118 increased mitochondrial respiration which was linked to phosphorylation by the ATP-synthase and alleviated the increase in lactate production induced by toxic doses of metformin. The redox agent methylene blue, in contrast, failed to mitigate the metformin-induced changes in mitochondrial respiration and lactate generation. Quote Link to comment Share on other sites More sharing options...
Ron Put Posted September 18, 2023 Report Share Posted September 18, 2023 Quote Link to comment Share on other sites More sharing options...
IgorF Posted September 19, 2023 Report Share Posted September 19, 2023 imho, the fact of existence of things like this https://www.amazon.com/Ultimate-Guide-Methylene-Blue-Mitochondrial/dp/177723963X should be a kind of a warning a quick search reveals that the substance was widely used for many decades for research support purposes, thus if there could be some strange effect easily reachable without a special delivery vehicle I would expect already more impressing results and studies, otherwise it looks like no one noticed something promising but off course I could be wrong with it, for the same probabilistic reasons.. Quote Link to comment Share on other sites More sharing options...
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