Clinton Posted February 20, 2021 Report Share Posted February 20, 2021 (edited) We know that the germline (sperm, eggs) are immortal (do not age) in the sense that each sperm or egg cell is young regardless of the age of the parent organism. These cells can create life and begin the life cycle again- from the beginning- without any record of the accumulated aging damage or methylation of the parent organism. It was logical then to search for the ‘fountain of youth’ in the germline. We realized that these cells do not lose telomeres or have very long telomeres due to plenty of telomerase... It appears however that telomeres are more of an indicator of cellular age than a cause or a control of it ... I can’t help but think that the secret to cracking the aging code is still in the germline despite the fact that telomeres/telomerase was not it. Edited February 20, 2021 by Clinton Quote Link to comment
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