martin knight
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From what I remember of the discussions on the email list over longevity benefits of exercise vs CR there wasn't much of a conclusion but the rodent evidence tended toward exercise not helping for a given bodyweight (i.e. increased intake to counter the extra expenditure) and even for no compensating increase in intake leading to decreased weight. Why body heat production - which is akin to exercise it seems to me - would be different is a mystery.
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Thanks Dean, that is a remarkable result and quite counter-intuitive. I will make one quibble: the longest lived 1/3 or so of the ERI (warm housed) mice - those who presumably adapted well to the diet - did live longer (about 1100 days) than the equivalent 1/3 of the controls (900) if not the ER (cooler housed but fed more) mice (1250). BTW I'm getting a site in Russian when I click on links to papers so am hesitant to proceed further :)
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But are mice in the TNZ in CR at all as they are no longer spending so much energy heating their bodies? Is there an experiment that compared raising mice in TNZ and below TNZ that calibrated intake so the two groups weighed the same? This would be better for our purposes as it would - for a given bodyweight - compare the decision to eat more to combat cold to eating less but staying warm.