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  1. Past hour
  2. find . -type f -exec grep -l "In order to continue, you need to verify that you're not a robot by solving a CAPTCHA puzzle" {} \; | wc -l 2310 Ugh add -exec rm {} + to delete (WITHOUT the wc -l) I'm going to try to rerun now, there's been some time passed since I last did it.
  3. Yesterday
  4. What about the confounder wherein low ldl levels occur with illnesses. I thought that was part of the problem with these studies. Many issues like malnutrition, cancer etc can cause lower ldl levels which would associate it with higher mortality but not be a cause
  5. Last week
  6. Earlier
  7. Last summer I rigged up a pool in the garden, for my son. However, he only used it a couple of times. So, I'm presently using it as a cold plunge. The temperatures are dropping and the water starts feeling coldish. Especially so this morning. I'm going to buy a water thermometer and some cleaning tools. And keep using it until possible or feasible. The plunge sure feels great but afterwards at times I feel myself anomalously hungry.
  8. (a bit ironically) - metformin of 2024 is semaglutid %) but seriously - I personally hope both these tools could help move forward in research (in addition to do some good work as drugs for those who could benefit of them
  9. I'll have to buy a suitable dynamometer. Only issue with this kind of measurements is that, it is not a constant, with training you can improve your grip strength substantially. Does this improve your mortality HR in a few weeks? And what if you have to discontinue training? Does it worsen your mortality HR in a short time?
  10. Based on the 900-day rule (which Kaberlein was a co-author), only 40% CR extended lifespan in the above-study... But the 40%CR group also faster for 2 days/week...
  11. while thinking about feasibility of adding back some bakery into my diet to substitute fruits partially I used to do some free search and unexpectadly landed into a book "Nutrition, Food and Diet in Ageing and Longevity" Springer Nature, 2021 from which I became curious about the research done by Grant Rutledge (https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0240132&type=printable) which focused on so called Hamilton's hypothesys (which supports a lot of observations and recommendations about dietary choices in the midlife given in some sane books like those by Fontana and other respected authors). In a few words - after 40 years of selective experiments on melanogasters it looks plausible to hypothesise that "ancestral" diet (the one adopted 90%+ of the species timeline) could be preferential from the midlife in comparison to the novel one of the recent generations. Here is a talk on the topic: I wonder if somebody from the long-term practitioners have own data on inflamation markers being on a healthy diet with grains/cereals and without them, offcourse no artificial "foods" or keto regimens and other known modifiers (e.g. huge o6 intake that could also interfer). The experiment could take many months, thus it could be useful to learn other's anecdotes on the topic. UPDATE: a systematic review on crp and il6 markers during grain/nograin studies https://pmc.ncbi.nlm.nih.gov/articles/PMC8778110/ (seems in all the experiments it does matter what was the type of diet, some have clear zero effect and some halves the markers easily)
  12. https://github.com/mendableai/firecrawl https://forum.cloudron.io/topic/12140/firecrawl-on-cloudron-turn-any-site-into-llm-data-by-web-scraping/3 Claude Sonnet 3.5.1 has VERY interesting code I should try.
  13. I started to supplement with L-carnosine, as part of Sandra Kauffman's Panacea protocol, which I modified a little. Kauffman's model is conceptually satisfying and she has cited a lot of research An interesting video on L-carnosine.
  14. I started to post in that forum as well, it's more oriented to pharmacological interventions for longevity and the detail in this regard is extreme, the latest research is published and discussed with all minutiae.
  15. There doesn't seem to be a video about his opinion on the China Study. Wish he'd do one on that.
  16. https://x.com/georgejrjrjr/status/1848410673564229707 i also use whole foods tea bc im often lazy
  17. https://www.sciencedirect.com/science/article/pii/S0304389421031216 Cotton and wood are biopersistent IN HUMAN TISSUE too. It's this kind of study that makes me panic about microplastics less, even *after* that infamous 2024 "microplastics in brains" study [it seems that this year is confirming our worst fears about MPs **and worse**], but it's still possible that microplastics may be unusually likely to lodge in the brain relative to wood/cotton - I don't know. Wood cellulose fibers persist in rat lungs after 1 year, higher bio-persistence compared to asbestos. Estimated half-life about 3 years (Muhle et al., 1997)
  18. I went an oxford instruments event today! Edinburgh instruments has a v. good channel https://scix2024.eventscribe.net/SearchByExpoCompany.asp?pfp=BrowseByCompany there are also mit.nano events
  19. the vast majority of CR practitioners I know don't look young for their age, even if their superficial biomarkers are good. I know there are many interactions with genetic background that may make this more true for some than others (I suspect that overall, genetics >> diet if you're eating a very healthy diet). I say this as someone who has always defended CR against others. [I also find CR hard to practice and often signalled doing CR when I wasn't - my level of neuroticism is too high for CR w/o retatrutide to be a realistic option]
  20. At what nm wavelength? I know different PBM devices use different wavelengths (longer wavelength can go deeper but scatters more). Shorter ones might work if they're inserted through the nose like Neuronic. I tried a couple of those devices at #ISNR2024 but didn't feel any different
  21. the 6th is most informative. uV values are important for many reasons (they're important for tracking brain health) [there are also some separate ICA images too] CHAL_NG_1.bmp CHAL_NG_2.bmp CHAL_NG_3.bmp CHAL_NG_4.bmp CHAL_NG_5.bmp CHAL_NG_6.bmp CHAL_NG_7.bmp CHAL_NG_8.bmp CHAL_NG_9.bmp CHAL_NG_10.bmp CHAL_NG_11.bmp CHAL_NG_12.bmp CHAL_NG_13.bmp
  22. livingthecrway.com doesn't have its forums anymore, and seems to be much more gated/paywalled than it used to be...
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